Searchable abstracts of presentations at key conferences in endocrinology

ea0065p7 | Adrenal and Cardiovascular | SFEBES2019

ULTRADIAN adrenal steroid metabolodynamics successfully discriminates pituitary Cushing’s disease from healthy normal variation

Upton Thomas , Zavala Eder , Fraser Diane , Methlie Paal , Russell Georgina , Tsagarakis Stelios , Kampe Olle , Lightman Stafford , Husebye Eystein

Background: Establishing endocrine diagnoses including pituitary Cushing’s remains challenging with delayed or misdiagnosis being very costly for both patient and the health care system. A key issue is that standard diagnostic tests are typically single time point, single analyte samples, which do not consider dynamic variation intrinsic to endocrine systems. Having previously demonstrated that free tissue hormones correlate strongly with plasma concentrations, we present...